Eye Injections

Understanding Age-Related Macular Degeneration (AMD) and Its Treatments

By Dr Parth Shah · 29 June 2026 · 9 min read

Dr Parth Shah
Dr Parth Shah
29 June 2026 Updated 29 June 2026 9 min read
Medically reviewed by Dr Parth Shah
Quick Answer
AMD is a progressive condition affecting central vision, common after age 50. There are two types: dry AMD(80–90% of cases, gradual) and wet AMD(faster, more severe, caused by abnormal blood vessels). Dry AMD is managed with supplements, diet and lifestyle changes; wet AMD is treated with anti-VEGF injections. Lost vision usually can't be fully restored, which is why early detection matters.

What Is Age-Related Macular Degeneration?

AMD is a chronic, progressive condition affecting the macula — the central part of the retina responsible for sharp, detailed, colour vision. It affects your central vision while leaving peripheral sight intact, impacting your ability to read, recognise faces and drive. AMD doesn't cause total blindness, but it significantly affects daily life, and is one of the most common causes of vision loss in adults over 50.

Dry AMD vs Wet AMD

Dry AMD (Atrophic)Wet AMD (Neovascular)
How common80–90% of AMD cases10–20% of AMD cases
How it progressesGradual, often unnoticed early onFaster, more severe vision loss
What causes itThinning macular tissue and drusen depositsAbnormal blood vessels leaking fluid or blood
Main treatmentSupplements, diet, lifestyle changesAnti-VEGF injections

Early Signs & Symptoms

  • • Blurred or distorted central vision
  • • Straight lines appearing wavy
  • • Colours looking dull
  • • Dark or empty patches in the centre of your vision
  • • Difficulty reading, driving at night, or recognising faces

AMD can progress silently

Routine eye exams after age 50 are the most reliable way to catch AMD before it significantly affects your vision.

Noticing changes in your central vision?

Early detection makes a real difference in preserving your sight — book a comprehensive eye exam.

Risk Factors

Age over 50, increasing significantly after 60Family history and geneticsSmoking — up to 4x higher riskLow antioxidant and omega-3 intakeHigh blood pressure, obesity or high cholesterolProlonged UV light exposure

How AMD Is Diagnosed

OCT Scan

High-resolution imaging of the retinal layers.

Fundus Photography

Detailed photos of the back of the eye for ongoing monitoring.

Fluorescein Angiography

A safe dye highlights leaking vessels in wet AMD.

Amsler Grid & Acuity Testing

Checks for central vision distortion and sharpness.

Treatment Options

For Dry AMD

  • • AREDS2 nutritional supplements
  • • Diet rich in leafy greens, colourful fruit and oily fish
  • • Smoking cessation and blood pressure management
  • • Low vision aids such as magnifiers

For Wet AMD

  • • Anti-VEGF injections to stop abnormal vessel growth
  • • Laser therapy to seal leaking vessels in selected cases
  • • Photodynamic therapy for certain presentations

In most cases lost vision can't be fully restored, but early detection preserves remaining vision and prevents further deterioration — wet AMD patients often regain some clarity after anti-VEGF therapy.

Conclusion

AMD is common, but it doesn't have to mean losing your independence. With regular eye exams after 50, early detection, and the right combination of lifestyle changes or treatment, most people continue to lead active lives. If you notice sudden distortion, blurred central vision or a dark patch, see an ophthalmologist promptly.

Frequently Asked Questions

Yes, though it typically begins in one eye first. Catching it early in the first eye can help prevent significant loss in the second.

Dr Parth Shah

Written by

Dr Parth Shah

Dr Parth Shah is director and principal ophthalmologist at Clarity Eye Surgeons, specialising in eye injections for retinal disease including AMD.

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